Author

Thomas Watson

The Francis Crick InstituteORCID 0000-0003-2074-7788Unclaimed ORCID profile · follow to get notified of new preprints

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Thomas Watson1 paper · Northwestern University

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:experimental assay· 1

Frequent Co-Authors

James BriscoeiD· 3 shared Mina GoutiiD· 2 shared Vicki MetzisiD· 2 shared Andreas SagneriD· 1 shared Despina Stamataki· 1 shared Edvinas Pakanavicius· 1 shared Harshil PateliD· 1 shared Isabel ZhangiD· 1 shared

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2018-2021 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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3 shared papersDevelopmental Biology

James BriscoeORCID

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3 papers

Recent·Most cited

Developmental BiologyPLoS BiologyPeer-reviewedNov 12, 2021

Temporal patterning of the central nervous system by a shared transcription factor code

Andreas Sagner, Isabel Zhang, Thomas Watson…·James Briscoe

The paper identifies a temporal patterning program in vertebrate neurons controlled by transcription factors and the TGFβ pathway, showing its role in generating neuronal diversity.

128 citationstop 2%

𝕏 PostBluesky

Developmental BiologybioRxivPreprintDec 29, 2020

Sox2 levels configure the WNT response of epiblast progenitors responsible for vertebrate body formation

Robert A. Blassberg, Harshil Patel, Thomas Watson…·James Briscoe

The paper shows that Sox2 levels determine how WNT signaling affects epiblast progenitors, influencing pluripotency and mesodermal differentiation through changes in chromatin occupancy and regulatory element selection.

14 citations

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Developmental BiologyCellPeer-reviewedOct 18, 2018

Regionalization of the nervous system requires axial allocation prior to neural lineage commitment

Vicki Metzis, Sebastian Steinhauser, Edvinas Pakanavicius…·James Briscoe

The paper challenges the established model of neural induction by showing that cells commit to anterior or posterior regional identities before acquiring neural identity.

159 citationstop 2%

ChIP-seqstatistical model

𝕏 PostBluesky