Author

Jin Lee

University of California San DiegoORCID 0000-0003-2124-4963Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jin Lee4 papers · Johns Hopkins University

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Gen‐Sheng FengiD· 3 shared Aaron P. HavasiD· 2 shared Adarsh RajeshiD· 2 shared Armin GandhiiD· 2 shared Jessica M. ProulxiD· 2 shared Karl N. MilleriD· 2 shared Marcos Garcia TenecheiD· 2 shared Peter D. AdamsiD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Gen‐Sheng FengORCID

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3 papers

Recent·Most cited

Rapamycin Reverses the Hepatic Response to Diet-Induced Metabolic Stress That Is Amplified by Aging.

Aaron P. Havas, Adarsh Rajesh, Xue Lei, Jessica M. Proulx, Karl N. Miller, Adam E. Field, Andrew Davis, Marcos G. Teneche, Armin Gandhi, Jin Lee, Gen‐Sheng Feng, Peter D. Adams

This study shows that rapamycin reduces age-related liver damage caused by a high-fat diet in mice by reversing transcriptional changes and metabolic dysfunction.

Aging Cell · Feb 1, 2026Peer-reviewedCell Biology

Activated Interferon Signaling Suppresses Age-Dependent Liver Cancer

Aaron P. Havas, Kathryn Lande, Adarsh Rajesh, K. Garrett Evensen, Siva Karthik Varanasi, Linshan Shang, Elizabeth K. Schmidt, Jin Lee, Kenneth H. Kim, Marcos Garcia Teneche, Filipe Araujo Hoffmann, Michael LaPorte, Andrew E. M. Davis, Abby Grier, Julie A. Reisz, , Peter D. Adams

This study shows that aged livers have heightened interferon signaling that suppresses cancer but also has harmful effects, leading to a 'precarious balance' in tumor development.

bioRxiv · Jul 31, 2024 · PreprintCancer Biology

Temporal Analyses of Postnatal Liver Development and Maturation by Single Cell Transcriptomics

Yan Liang, Kota Kaneko, Xin Bing, Jin Lee, Xin Sun, Kun Zhang, Gen‐Sheng Feng

The paper uses single-cell transcriptomics to analyze liver development in mice, identifying cell types, metabolic zonation, and a transient macrophage population.

Developmental Cell · Feb 1, 2022Peer-reviewedDevelopmental Biology