Joseph W. Gordon

BCL2L13 attenuation links impaired mitophagy to epithelial plasticity and anoikis tolerance in lung adenocarcinoma

This study shows that BCL2L13 downregulation in NSCLC promotes metastasis by impairing mitophagy and enhancing epithelial plasticity and anoikis tolerance.

Human breast milk extracellular vesicles from mothers with asthma differentially modulate the release of inflammatory cytokines by primary human airway smooth muscle cells in a recipient-cell specific manner

This study shows that breast milk extracellular vesicles from mothers with asthma differentially modulate cytokine release by airway smooth muscle cells depending on the donor and recipient cell type.

Chronic contractile activity induced skeletal muscle-derived extracellular vesicles increase mitochondrial biogenesis in recipient myocytes via transmembrane or peripheral membrane proteins

Identification of novel myokines and putative protein targets that mediate functional adaptations in response to chronic contractile activity induced skeletal muscle-extracellular vesicle treatment

The paper identifies novel proteins and pathways in skeletal muscle-derived extracellular vesicles following chronic contractile activity, suggesting their role in metabolic and anti-tumorigenic effects.

The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

This study shows that chronic contractile activity-induced skeletal muscle-derived extracellular vesicles reduce LLC cell viability and induce apoptosis and senescence.

Assessment of Stiffness-Dependent Autophagosome Formation and Apoptosis in Embryonal Rhabdomyosarcoma Tumor Cells

This study evaluates how matrix stiffness affects autophagosome formation and apoptosis in embryonal rhabdomyosarcoma cells using GelMA hydrogels.