Author

Jayati L. Chakrabarti

University of ArizonaORCID 0000-0003-2265-4657Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:imaging· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:spatial transcriptomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Kelvin W. PondiD· 2 shared Meenu Priya ResmiiD· 2 shared Saptarshi MallickiD· 2 shared Abigail G. Branch· 1 shared Alexander Borowiec· 1 shared Curtis A. ThorneiD· 1 shared Elliott B. BurdetteiD· 1 shared Eugene DouglassiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBioengineering

Kelvin W. PondORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 7, 2026

Patient-Derived Organoids as a Model to Understand Tumor Microenvironment-Driven Nano-Bio Interactions - A Framework Towards Improved Nanomedicine Translation

Meenu Priya Resmi, Jayati L. Chakrabarti, Kelvin W. Pond, Swarna Ganesh

This paper uses patient-derived colonic organoids to study how tumor microenvironment proteins affect nanoparticle uptake and delivery, showing improved targeting of chemoresistant cells.

DOI 10.64898/2026.09.03.749195

humanspatial transcriptomics

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Cell BiologybioRxivPreprintApr 11, 2026

Preservation of Human Colonic Stem Cells Requires an ERK Dynamics Checkpoint Mediated by AKT

Lauren Riede, Alexander Borowiec, Saptarshi Mallick…·Kelvin W. Pond

The paper shows that human colonic stem cells use an AKT-dependent ERK dynamics checkpoint to maintain tissue homeostasis by suppressing differentiation-inducing ERK pulses.

DOI 10.64898/2026.04.02.715982

humanproteomics

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Cancer BiologybioRxivPreprintMay 22, 2025

Spatial Biology and Organoid Technologies Reveal a Potential Therapy-Resistant Cancer Stem Cell Population in Pancreatic Ductal Adenocarcinoma

Pritha Adhikary, Jayati L. Chakrabarti, Saptarshi Mallick…·Yana L. Zavros

The paper uses spatial imaging and organoid models to identify therapy-resistant CD44v9+ cancer stem cells in PDAC and show that cabozantinib may enhance immunotherapy by altering the tumor microenvironment.

1 citation

humanspatial transcriptomics

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