Qiumin Tan

This study shows that CIC deletion causes abnormal mossy fiber targeting in the mouse hippocampus after the second postnatal week, due to loss of a mature granule neuron subtype and dysregulation of axon guidance genes.

This study investigates how MATR3 variants affect cryptic splicing repression, showing that some variants reduce protein solubility and impair RNA binding and splicing regulation.

This study shows that human CD33 isoforms differentially affect microglial responses in Alzheimer's disease, with CD33m showing protective effects against amyloid-beta pathology.