Meriem El Karoui

The paper quantifies the antagonistic interaction between ciprofloxacin and tetracycline at the single-cell level in Escherichia coli, showing that improved growth under the combination is due to increased survival of cells with low SOS response.

This paper uses deep variational autoencoders to learn representations of single-cell time-series data from E. coli, showing good generalization across growth conditions and drug treatments.

This paper develops a unified mathematical framework to compare models of DNA replication and cell division coordination in E. coli, finding that a double-process model better explains experimental data across growth conditions.

This study quantifies RecB dynamics at DNA double-strand breaks in E. coli, showing long-lived complexes and intrinsic dissociation properties, and uses RecB binding to estimate damage formation rates.

This study uses single-molecule imaging in E. coli to show that RecB facilitates efficient DNA repair without activating the SOS response, while a modified RecB leads to less efficient repair and high SOS induction.

The paper shows Hfq regulates RecB protein levels in E. coli by reducing translation of recB mRNA, maintaining optimal RecB abundance.

The paper quantifies very low-abundant proteins in bacteria using HaloTag and epifluorescence microscopy, achieving ≥80% detection efficiency.