Author

Devon Duron Ehnes

University of WashingtonORCID 0000-0003-2575-8048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashish PhaliD· 2 shared Hannele Ruohola‐BakeriD· 2 shared Julie MathieuiD· 2 shared Aishwarya A. GogateiD· 1 shared Akira MorishitaiD· 1 shared Ammar AlghadeeriD· 1 shared AP Patni· 1 shared Arikketh DeviiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersDevelopmental Biology

Ashish PhalORCID

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2 papers

Recent·Most cited

Human iPSC-derived salivary gland organoids model diabetic salivary gland dysfunction

Devon Duron Ehnes, Akira Morishita, Ashish Phal, Hee Yun Jung, Yen Chian Lim, Zachary Foreman, Vincenzo Cirulli, Julie Mathieu, Hannele Ruohola‐Baker

This study develops human iPSC-derived salivary gland organoids that model diabetic dysfunction, showing impaired oxidative phosphorylation and FOXO1 nuclear localization in response to Metformin.

bioRxiv · Oct 1, 2025 · PreprintDevelopmental Biology

Human iPSC Derived Enamel Organoid Guided by Single-Cell Atlas of Human Tooth Development

Ammar Alghadeer, Sesha Hanson-Drury, Devon Duron Ehnes, Yan Ting Zhao, AP Patni, Diana R. O’Day, CH Spurrell, Aishwarya A. Gogate, Ashish Phal, H. Zhang, Arikketh Devi, Yuliang Wang, Lea M. Starita, Dan Doherty, Ian A. Glass, , Hannele Ruohola‐Baker

The paper establishes a single-cell atlas of human tooth development and uses it to guide the in vitro differentiation of ameloblasts from iPSCs, developing a mineralizing enamel organoid system.

bioRxiv · Aug 9, 2022 · PreprintDevelopmental Biology