Fanny Boulet

Acute BRD4 degradation and BD2 mutations de-repress bivalent developmental and neuronal genes in human stem cells and organoids, consistent with BRD4 recruitment by H3K14ac/H3K23ac and interaction with PRC1.6.

The paper develops AI models to predict enhancers in human and mouse cell lines, identifying H3K18ac as a new enhancer marker and annotating enhancers using a combination of epigenetic marks.

This study identifies a transposable element (TE) signature in maternal cell-free RNA that predicts preeclampsia with high accuracy.

This study shows PSIP1 reduces R-loops at transcription sites, preventing DNA damage and maintaining genome integrity in human and mouse cells.

The paper shows H4K16ac activates LINE1 and LTR transcription, contributing to cis-regulatory function by maintaining active chromatin at TEs.

This study identifies regulatory de novo mutations in fetal brain-specific enhancers as a significant contributor to intellectual disability.