PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity
Sundarraj Jayakumar, Manthan Patel, Fanny Boulet, Hadicha Aziz, Greg Nicholas Brooke, Hemanth Tummala, Madapura M. Pradeepa
This study shows PSIP1 reduces R-loops at transcription sites, preventing DNA damage and maintaining genome integrity in human and mouse cells.
Nature Communications · Jan 8, 2024Peer-reviewedMolecular Biology