Author

Francesca Malerba

European Brain Research InstituteORCID 0000-0002-8635-8622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Antonino CattaneoiD· 2 shared Simona CapsoniiD· 2 shared Brian P. HafleriD· 1 shared Carla PetrellaiD· 1 shared Chiara MorelliiD· 1 shared Cinzia SeveriniiD· 1 shared Francesco OlimpicoiD· 1 shared Gerard WalkeriD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Antonino CattaneoORCID

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2 papers

Recent·Most cited

A painless nerve growth factor variant uncouples nociceptive and neurotrophic TrkA signaling

Shailesh Kumar, Harry Jung, Gerard Walker, Jaimin K. Rana, Rui Fu, Minh Triết Hồng, Francesca Malerba, Jyotsna Kumar, Vikas Navratna, Wonhyeuk Jung, Sean Miller, Lukas M. Kruckenhauser, Simona Capsoni, Brian P. Hafler, Antonino Cattaneo, , Moitrayee Bhattacharyya

This paper identifies a NGF variant that selectively biases TrkA signaling towards neurotrophic functions without triggering pain, revealing mechanisms for therapeutic targeting of the NGF-TrkA pathway.

bioRxiv · Nov 18, 2025 · PreprintNeuroscience

A congenital pain insensitivity mutation in the nerve growth factor gene uncouples nociception from affective pain in heterozygous humans and mice

Giovanna Testa, Irene Perini, Marco Mainardi, Chiara Morelli, Francesco Olimpico, Laura Pancrazi, Carla Petrella, Cinzia Severini, Rita Florio, Francesca Malerba, Paul A. Heppenstall, Mario Costa, India Morrison, Simona Capsoni, Antonino Cattaneo

This study investigates how congenital pain insensitivity in heterozygous humans and mice affects affective pain responses, finding dissociated effects on learned fear and neural processing.

bioRxiv · May 25, 2018 · PreprintNeuroscience