Benjamin Audit

The paper develops a method to create high-resolution single-molecule replication maps of the human genome using multipulse BrdU labelling and ForkML.

This paper introduces a Bayesian model for DNA replication that infers origin timing and activation delays using RFD data, revealing 150 origins with significant delays in yeast.

This paper extends Modular Response Analysis to account for global perturbations and improves robustness in inferring gene regulatory networks.

Nanotiming provides high-resolution telomere-to-telomere replication timing profiles using nanopore sequencing, validated in yeast with cost and simplicity advantages.

The paper investigates how DNA sequence and epigenetic marks influence nucleosome positioning and breathing by analyzing NIEBs, NDRs, and nucleosome size in mouse chromatin.

FORK-seq maps DNA replication at single-molecule resolution in yeast, revealing previously missed initiation and termination events.

The paper uses nanopore sequencing and a neural network to identify BrdU-labelled DNA tracts in yeast during replication, showing they align with early-firing origins.