Christoph Crocoll

The paper develops orthogonal quorum sensing circuits in yeast using LuxR-type systems to enable programmable intercellular communication for synthetic biology applications.

This paper demonstrates the production of galantamine in yeast through pathway engineering and optimization, achieving a 173-fold improvement over the parental strain.

This study identifies gene expression markers and glucosinolate profiles associated with resistance to Pyrenopeziza brassicae in Brassica napus.

This study evaluates how adding raw rapeseed press cake to snack bars affects sensory qualities and identifies bitter compounds responsible for the taste.

This paper optimizes the glucosinolate biosynthesis pathway in E. coli to produce simple glucosinolates with high titers, achieving a 500-fold increase over yeast production.

The paper introduces an untargeted method to expand and compare substrate spectra of plant transporters using metabolite accumulation patterns in Xenopus laevis oocytes.

The paper investigates how two plant glucosinolate transporters (GTRs) recognize and transport different substrates by mutating residues and analyzing their effects on substrate preference.

This paper demonstrates the feasibility of engineering 2-phenylethylglucosinolate production in Nicotiana benthamiana by combining biosynthetic genes from Barbarea vulgaris and Arabidopsis thaliana, resulting in increased 2PE yield through chimeric pathway optimization.

The paper identifies a phlorizin transporter from Arabidopsis and shows its application in increasing phlorizin production in yeast.

This study optimizes benzylglucosinolate production in yeast by comparing plasmid and genome integration methods and enhancing key enzymes in the biosynthetic pathway.