Author

Elliott M. Bernard

University of LausanneORCID 0000-0003-2761-3790Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Petr BrožiD· 2 shared Alexandra BoegliiD· 1 shared Camilo PéreziD· 1 shared Christian SiebeniD· 1 shared Daniel J. MülleriD· 1 shared Dimitrios Fotiadis· 1 shared Ella HartenianiD· 1 shared Gaël Majeux· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Petr BrožORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 23, 2025

Sterile- or pathogen-induced endolysosomal damage activate the NLRP6 inflammasome in human intestinal epithelial cells

Alexandra Boegli, Elliott M. Bernard, Louise Lacante…·Petr Brož

This study shows that NLRP6 inflammasome activation in human intestinal epithelial cells occurs due to endolysosomal damage from pathogens or sterile triggers, leading to pyroptosis.

1 citation

humanproteomics

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ImmunologybioRxivPreprintOct 29, 2024

Membrane Tension Drives Opening of NINJ1 Lesions in Dying Cells

Ella Hartenian, Elliott M. Bernard, Giulia E. M. Ammirati…·Petr Brož

This study shows membrane tension drives NINJ1 filament opening, causing cell lysis, and explains why NINJ2 fails to form lesions.

11 citations

experimental assaymechanistic / dynamical model

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