Devin Wahl

This study shows apigenin extends healthspan and protects against Alzheimer's proteotoxicity in C. elegans by reducing oxidative stress and improving physiological function.

This study shows that Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function in aged and tauopathy mouse models.

This paper demonstrates that NI112, a brain-penetrant Nanoligomer targeting NF-κB and NLRP3, improves functional outcomes and reduces neuroinflammation in ALS and AD human organoid and mouse models.

The paper investigates how healthy aging interventions affect non-coding repetitive element transcripts in mice and humans, finding they are globally reduced by interventions and increased by aging.