Author
Wuhan UniversityORCID 0000-0003-2811-2656Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Xionglue Wang, Jie Li, Zhichao Liu…·Bin Zhu
The paper shows that Co2+ and Ni2+ activate coronavirus nsp15, while Zn2+ inhibits it, and explains the structural basis for this activity.
Yan Yan, Xiang Li, Shuaihua Zhang…·Bin Zhu
The paper identifies a regulatory mechanism that tunes cGAS signaling by cleaving a catalytic intermediate, preventing excessive activation while preserving immune function.
Setu M. Vora, Pietro Fontana, Tianyang Mao…·Hao Wu
SARS-CoV-2 5' UTR stem-loop 1 (SL1) lets reporters escape Nsp1 translational shutdown. LNA antisense oligos against SL1 restore Nsp1 suppression and reduce infected Vero E6 cells.