Xiang Li

The paper identifies C/D box snoRNAs, including orphans, that are involved in fear-related memory processes in mice by modulating mRNA methylation and synaptic function.

This study identifies Vaultrc5 as a noncoding RNA that regulates synaptic vault trafficking and RNA cargo dynamics, impacting learning and memory.

The paper identifies local translation of circular RNAs in the prefrontal cortex of mice, revealing a micropeptide involved in synaptic activity and memory.

The paper identifies a brain-enriched extrachromosomal circular DNA (ecDNA) that regulates plasticity-related genes and is linked to fear memory stability in mice.

The paper integrates multi-omic data from mouse and human prefrontal cortex subregions to identify cell-type-specific PTSD risk factors and regulatory landscapes.

The paper identifies a regulatory mechanism that tunes cGAS signaling by cleaving a catalytic intermediate, preventing excessive activation while preserving immune function.

starTracer improves marker gene identification in single-cell RNA-seq by enhancing specificity and speed compared to Seurat.

This study shows that TRPV4 knockdown improves fear memory deficits caused by acute sleep deprivation by reducing Ca2+ overload and restoring synaptic plasticity.

The paper shows that inhibiting the CPEB3 ribozyme increases CPEB3 protein and enhances memory by promoting mRNA polyadenylation and translation.

The paper identifies a lncRNA, Gas5, involved in fear extinction by regulating RNA granule trafficking and clustering at synapses in mice.

The paper identifies synapse-specific m6A RNA readers and their role in fear extinction memory consolidation through RNA immunoprecipitation and sequencing in mice.

The paper identifies ADRAM, an experience-dependent lncRNA that interacts with 14-3-3 to regulate Nr4a2 expression and fear extinction memory in mice.

The paper shows that the CPEB3 ribozyme regulates hippocampal-dependent memory by modulating mRNA maturation and translation of plasticity-related genes.

This study shows ADAR1 interacts with Z-DNA during fear extinction learning, affecting RNA editing and memory flexibility.

This study shows that m6dA accumulation in DNA of prefrontal cortical neurons is linked to fear extinction learning and gene expression.

This study shows that knocking down Piwil1 and Piwil2 in the mouse hippocampus enhances contextual fear memory without affecting anxiety.

This paper identifies Gadd45g as a regulator of IEG expression dynamics and memory consolidation through DNA methylation changes during fear learning.

This study shows that ING1 regulates activity-induced gene expression in cortical neurons by interacting with other epigenetic factors and affecting synaptic plasticity-related genes.