Giovanna Brancati

This paper introduces a high-throughput histopathology workflow for complex in vitro models using 3D-printed histomolds, enabling efficient processing and analysis of multiple samples.

The paper develops a linear model to predict chromatin dynamics based on transcription factor binding in C. elegans, identifying key regulators that schedule gene expression rhythms.

Phospho-seq integrates phosphorylated protein profiling with scATAC-seq and scRNA-seq to study cell signaling and gene regulation in single cells.

This paper develops a multimodal approach to study human retinal organoid development, integrating spatial, transcriptomic, and chromatin accessibility data to create a virtual atlas of retinal development.

The paper shows that miRNA activity and specificity depend on both target site architecture and miRNA abundance, challenging the binary view of target site functionality.