Tyler Jackson

This study uses in-situ glial cell-surface proteomics in Drosophila to identify DIP-β as a pro-longevity factor regulated by glial cells.

This study presents a single-nucleus transcriptomic atlas of Drosophila treated with rapamycin, identifying a sex-biased convergent aging trajectory and its modulation by rapamycin.

This study identifies Cph as a key regulator of intestinal stem cell proliferation and differentiation, showing its role in maintaining ISC and EE populations and remodeling progenitor transcriptomes.

This study identifies Tet as a critical regulator of intestinal stem cell establishment and homeostasis through single-nucleus transcriptomic analysis.

The paper shows that injured Drosophila gut polyploid enterocytes dedifferentiate into diploid progenitors via paligenosis, involving autophagy and TORC1.

The paper uses snRNA-seq in Drosophila to study how AD-associated proteins affect peripheral tissues, finding distinct impacts of Aβ42 and Tau on sensory neurons and non-neuronal tissues.

The paper presents an aging Drosophila cell atlas, identifies cell type-specific aging patterns, and shows ribosomal gene expression as a conserved aging predictor.

The paper identifies MMBIR mutations in cancer and normal cells, showing their accumulation in cancer and disruption of tumor suppressor genes.