Author

Siamak Redhai

German Cancer Research CenterORCID 0000-0002-1202-9455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Michael BoutrosiD· 2 shared Michaela HolzemiD· 2 shared Svenja Leible· 2 shared Tianyu WangiD· 2 shared Christina KoiD· 1 shared David IbbersoniD· 1 shared Erica ValentiniiD· 1 shared Fillip PortiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersDevelopmental Biology

Michael BoutrosORCID

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2 papers

Recent·Most cited

Proliferation and differentiation of intestinal stem cells depends on the zinc finger transcription factor BCL11/Chronophage

Siamak Redhai, Nick Hirschmüller, Tianyu Wang, Tyler Jackson, Stefan Peidli, Erica Valentini, Shivohum Bahuguna, Svenja Leible, Sarina Möller, Christina Ko, Michaela Holzem, Sviatoslav Kharuk, Lea Bräckow, Fillip Port, David Ibberson, , Michael Boutros

This study identifies Cph as a key regulator of intestinal stem cell proliferation and differentiation, showing its role in maintaining ISC and EE populations and remodeling progenitor transcriptomes.

The EMBO Journal · May 20, 2026Peer-reviewedDevelopmental Biology

Direct detection of CRISPR mutations and transcriptional responses at single cell resolution in vivo

John A. Hawkins, Siamak Redhai, Svenja Leible, Mireia Osuna Lopez, Hilal Ozgur, Tianyu Wang, Michaela Holzem, Michael Boutros, Oliver Stegle

This paper introduces scPT-seq, a method to detect CRISPR mutations and transcriptional responses at single-cell resolution in vivo, revealing clonal markers and lineage dynamics in Drosophila intestine.

bioRxiv · Dec 24, 2025 · PreprintMolecular Biology