Author

Connie B. Nichols

Duke UniversityORCID 0000-0003-0092-0192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:fungi (other)· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. Andrew AlspaughiD· 2 shared Alexander R. Jenner· 1 shared Catherine A. Denning-JannaceiD· 1 shared Charles D. GiamberardinoiD· 1 shared Chloe Insler· 1 shared Christina Alexandre· 1 shared Clifford T. GeeiD· 1 shared Corinna ProbstiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

J. Andrew AlspaughORCID

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3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedJun 9, 2026

A cysteine-rich domain of the Cryptococcus neoformans Cuf1 transcription factor is required for high copper stress sensing and fungal virulence

Corinna Probst, Chloe Insler, Catherine A. Denning-Jannace…·J. Andrew Alspaugh

This paper identifies a cysteine-rich motif in CnCuf1 essential for high copper stress sensing in Cryptococcus neoformans, impacting fungal virulence and lung infection patterns.

1 citation

mousefungi (other)

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedAug 25, 2025

Inhibitors of trehalose-6-phosphate synthase activity in fungal pathogens compromise thermal tolerance pathways

Yi Miao, Vikas Yadav, William R. Shadrick…·E. Washington

This paper identifies 4456dh, a small molecule inhibitor of trehalose-6-phosphate synthase, which disrupts fungal thermal tolerance and virulence.

3 citations

fungi (other)experimental assay

𝕏 PostBluesky

GeneticsPLoS GeneticsPeer-reviewedFeb 15, 2024

CryptoCEN: A Co-Expression Network for Cryptococcus neoformans reveals novel proteins involved in DNA damage repair

Matthew J. O’Meara, Jackson R. Rapala, Connie B. Nichols…·Teresa R. O’Meara

CryptoCEN, a co-expression network for Cryptococcus neoformans, identifies 13 novel DNA damage repair genes with 100% predictive accuracy.

9 citations

fungi (other)bulk RNA-seq

𝕏 PostBluesky