Roberto Ciccocioppo

The paper uses Genomic SEM to identify loci underlying locomotor activity in rats, finding 31 loci compared to fewer from other methods.

This paper integrates longitudinal neuroimaging and microbiota data in rats to identify Akkermansia as a microbial modulator of alcohol-induced gut-liver-brain pathology and validates its therapeutic potential.

The paper introduces a machine learning model using 3D RCNN to automate behavioral analysis in the Forced Swim Test, accurately distinguishing swimming, climbing, and immobility behaviors in rodents.

This study introduces a no-timeout self-administration procedure to better mimic human heroin use patterns in rats, showing it alters heroin intake and social behavior but not cocaine use.

This study identifies genetic loci associated with opioid use disorder-related behaviors in rats using a genome-wide association approach and network-based clustering.

This study uses a non-linear clustering approach in rats to identify distinct behavioral and neuronal profiles associated with heroin vulnerability and resiliency, reflecting human opioid use disorder heterogeneity.

This study shows that long-access heroin self-administration in rats reduces grey matter volume in specific brain regions and alters microglia morphology, suggesting a link between neuroinflammation and structural brain changes.

This study shows that adolescent sleep restriction increases adult alcohol consumption by promoting risky behavior, using both human epidemiological data and preclinical experiments.