Massimo Ubaldi

Genomic SEM reveals shared genetic architecture and expands locus discovery for locomotor activity in heterogeneous stock rats

The paper uses Genomic SEM to identify loci underlying locomotor activity in rats, finding 31 loci compared to fewer from other methods.

Machine Learning-Based Model for Behavioral Analysis in Rodents: Application to the Forced Swim Test

The paper introduces a machine learning model using 3D RCNN to automate behavioral analysis in the Forced Swim Test, accurately distinguishing swimming, climbing, and immobility behaviors in rodents.

Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats

This study identifies genetic loci associated with opioid use disorder-related behaviors in rats using a genome-wide association approach and network-based clustering.

Long-access heroin self-administration induces region specific reduction of grey matter volume and microglia reactivity in the rat.

This study shows that long-access heroin self-administration in rats reduces grey matter volume in specific brain regions and alters microglia morphology, suggesting a link between neuroinflammation and structural brain changes.