Author

Gregory James Gores

Mayo ClinicORCID 0000-0003-3151-009XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Akhilesh PandeyiD· 2 shared Amro M. AbdelrahmaniD· 2 shared Danielle Marie CarlsoniD· 2 shared Dong‐Gi MuniD· 2 shared Enis H. OzmertiD· 2 shared Erik JesseniD· 2 shared Hendrien KuipersiD· 2 shared Jack W. SampleiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Akhilesh PandeyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ESCRT-dependent YAP degradation by AKT blockade overcomes adaptive resistance to RAS(ON) inhibition in pancreatobiliary cancer

Jack W. Sample, Enis Özmert, Brandon A. Wilbanks, Danielle Marie Carlson, Hidemi Nishi, Amro M. Abdelrahman, Erik Jessen, Meina Cai, Dong‐Gi Mun, Hendrien Kuipers, Anna Splinter, Alexander L. Ticho, Nathan W. Werneburg, Akhilesh Pandey, Mark Joseph Truty, , Rory L. Smoot

This study identifies AKT as a regulator of YAP stability and shows that AKT inhibition triggers ESCRT-dependent YAP degradation, enhancing the efficacy of RAS inhibition in pancreatobiliary cancers.

bioRxiv · Oct 20, 2026 · PreprintCancer Biology

CD4+ T cells promote fibrosis during metabolic dysfunction-associated steatohepatitis

Lucía Valenzuela-Pérez, Hyun Se Kim Lee, Rachel L. Bayer, Dina Faeq Manna, Shravan K. Mishra, Alexander M. Washington, AbidM Hassan, Malaz M. Sidahmed, Edward Ssali, Ece Janet Dinç, Benie K. Manwana, Ahmed Ibrahim, Qianqian Guo, Adam Herman, Rondell P. Graham, , Petra Hirsova

This study identifies CD4+ T cells as drivers of fibrosis in MASH by showing their proinflammatory activity and the therapeutic potential of targeting the OX40L-OX40 axis.

Hepatology · Apr 30, 2026Peer-reviewedImmunology

Multiomics-driven discovery of predictive biomarkers and strategies to overcome resistance to SFK-YAP inhibition in cholangiocarcinoma

Hendrien Kuipers, Danielle Marie Carlson, Erik Jessen, Aushinie M. Abeynayake, Jack W. Sample, Dong‐Gi Mun, Jennifer L. Tomlinson, Amro M. Abdelrahman, Nathan W. Werneburg, Binbin Li, Enis H. Ozmert, Caitlin B. Conboy, Mitesh J. Borad, Mark Joseph Truty, Akhilesh Pandey, , Rory L. Smoot

This study identifies biomarkers and resistance mechanisms to SFK-YAP inhibition in cholangiocarcinoma using multiomic profiling and shows synergy with chemotherapy.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology