Author

Carl J. Manner

Duke UniversityORCID 0000-0003-3162-1478Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alejandro BerríoiD· 1 shared David R. McClayiD· 1 shared Esther Miranda· 1 shared Gregory A. WrayiD· 1 shared Jacqueline A. BrinkmaniD· 1 shared Jesse R. RaabiD· 1 shared Keen Wilson· 1 shared Mallory SokolowskiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperDevelopmental Biology

Alejandro BerríoORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 12, 2026

Loss of cBAF Complex Confers Sorafenib Resistance in Liver Cancer

Jacqueline A. Brinkman, Margarita M. Dzama, Max Bucklan…·Jesse R. Raab

This study identifies the cBAF complex as a driver of sorafenib resistance in liver cancer by disrupting hepatocyte lineage identity and promoting a mesenchymal drug-tolerant state.

DOI 10.64898/2026.06.11.731725

humanChIP-seq

𝕏 PostBluesky

Developmental BiologyDevelopmental BiologyPeer-reviewedAug 3, 2024

An RNA interference approach for functional studies in the sea urchin and its use in analysis of Nodal signaling gradients

Keen Wilson, Carl J. Manner, Esther Miranda…·David R. McClay

This paper demonstrates the use of DsiRNA for functional studies in sea urchin embryos, showing its effectiveness in knocking down genes and analyzing Nodal signaling gradients.

4 citations

experimental assayperturbation response prediction

𝕏 PostBluesky