Author

Margarita M. Dzama

University of North Carolina at Chapel HillORCID 0009-0005-4347-0875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Jacqueline A. BrinkmaniD· 2 shared Jesse R. RaabiD· 2 shared Mallory SokolowskiiD· 2 shared Carl J. ManneriD· 1 shared Catharina Lahrmann· 1 shared Catherine WölfeliD· 1 shared Daniel SascaiD· 1 shared Evelyn UllrichiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Jacqueline A. BrinkmanORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 12, 2026

Loss of cBAF Complex Confers Sorafenib Resistance in Liver Cancer

Jacqueline A. Brinkman, Margarita M. Dzama, Max Bucklan…·Jesse R. Raab

This study identifies the cBAF complex as a driver of sorafenib resistance in liver cancer by disrupting hepatocyte lineage identity and promoting a mesenchymal drug-tolerant state.

DOI 10.64898/2026.06.11.731725

humanChIP-seq

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Cancer BiologybioRxivPreprintFeb 17, 2026

Menin-Inhibition Sensitizes Acute Myeloid Leukemia to CLEC12A-Directed CAR Cell Therapy

Johanna Rausch, Philipp Wendel, Margarita M. Dzama…·Michael W.M. Kühn

This paper shows menin inhibitors increase CLEC12A expression in AML, making it more responsive to CLEC12A-targeted CAR T cells, improving treatment outcomes.

DOI 10.64898/2026.02.15.703376

humanbulk RNA-seq

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Cancer BiologyCell ReportsPeer-reviewedNov 25, 2025

Menin-MLL1 complex cooperates with NF-Y to promote HCC survival

Margarita M. Dzama, Mallory Sokolowski, Peyton C. Kuhlers…·Jesse R. Raab

This study identifies the menin-MLL1 complex as essential for HCC survival and shows it cooperates with NF-Y to regulate oncogenic gene transcription.

3 citations

humanChIP-seq

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