Jonathan L. Koff

This study shows that a single crystalline silica exposure causes subclinical cardiopulmonary abnormalities in mice, with sex-dependent effects on lung mechanics and transcriptomic responses.

This study shows that EGFR regulates Beclin-1 and autophagy in hyperoxic acute lung injury, suggesting a novel therapeutic pathway.

This study investigates the prevalence and role of Staphylococcus aureus superantigens in CF lung disease, showing their ability to induce inflammatory responses in mouse models.

The paper identifies bacterial receptor genes determining phage host range, showing defense mechanisms are not predictive of susceptibility.

This study investigates how lytic bacteriophages interact with respiratory epithelial cells and their effects on cytokine secretion, highlighting the need to consider mammalian responses in phage therapy.