Huanxing Su

This study identifies Senescent Astrocytic Deposits (SAD) as a mechanism linking astrocyte senescence to synaptic dysfunction and cognitive decline in aging brains.

This study compares temporal transcriptomic changes in iPSC-derived motor neurons with SOD1 mutations D91A and G94A to understand their impact on ALS severity.

The paper shows that histone marks drive phase-separated chromatin compartments, influencing gene expression and cancer progression through the CBX7-PRC1 complex.

This study identifies a previously unrecognized CSF drainage pathway through blood vessels in the nasal mucosa, showing that CSF tracers can be drained via both lymphatic and venous routes in mice.