Bojana Stefanovska

This study shows that endogenous APOBEC3B causes DNA damage and replication stress, making cancer cells sensitive to CHK1 inhibitors.

This paper introduces collapsing retroviruses (CRVs) to deliver viro-toxic cargoes like APOBEC3B by using recombination to restore gene integrity during transduction, achieving near 100% efficiency.

HAMMER is a luminescence-based assay that measures APOBEC3A-mediated RNA editing by detecting changes in luciferase activity ratios.

This study identifies APOBEC3 mutagenesis as a common driver of therapy resistance in breast cancer, associated with poorer clinical outcomes.

The paper identifies CtBP2 as a key factor in CYR61-induced metastasis of osteosarcoma under non-hypoxic conditions.

This study shows that carcinogen-induced DNA adducts enhance APOBEC3B-mediated mutagenesis, leading to increased mutation rates in cancer genomes.