Author

Natalia Sikorska

Centre National de la Recherche ScientifiqueORCID 0000-0003-3333-697XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Tom SextoniD· 2 shared Anne Marie MolitoriD· 1 shared Chenfan Ji· 1 shared Ian C. TobiasiD· 1 shared Jennifer A. MitchelliD· 1 shared Lida LangroudiiD· 1 shared Marit A. C. de KortiD· 1 shared Nawrah KhaderiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenetics

Tom SextonORCID

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2 papers

Recent·Most cited

Transcriptional regulation and chromatin architecture maintenance are decoupled modular functions at the Sox2 locus

Tiegh Taylor, Natalia Sikorska, Virlana M. Shchuka, Sanjay Chahar, Chenfan Ji, Neil N. Macpherson, Sakthi D. Moorthy, Marit A. C. de Kort, Shanelle Mullany, Nawrah Khader, Zoe E. Gillespie, Lida Langroudi, Ian C. Tobias, Tineke Laura Lenstra, Jennifer A. Mitchell, Tom Sexton

The paper shows that transcriptional control and chromatin architecture at the Sox2 locus are decoupled, with distinct regulatory mechanisms.

Genes & Development · Jun 1, 2022Peer-reviewedGenetics

ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Yousra Ben Zouari, Anne Marie Molitor, Natalia Sikorska, Véra Pancaldi, Tom Sexton

ChiCMaxima detects and visualizes chromatin loops in Capture Hi-C data using local maxima and a background model, showing improved robustness over existing tools.

Genome biology · May 22, 2019Peer-reviewedGenomics