Author

Tiegh Taylor

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 4 Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Jennifer A. MitchelliD· 4 shared Ian C. TobiasiD· 2 shared Nawrah KhaderiD· 2 shared Sakthi D. MoorthyiD· 2 shared Shanelle Mullany· 2 shared Tom SextoniD· 2 shared Alisha Suri· 1 shared Azad AlizadaiD· 1 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersGenomics

Jennifer A. MitchellORCID

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Author profile →

5 papers

Recent·Most cited

Enhancers mediate euchromatin hopping at chromatin contact points

Shanelle Mullany, Tiegh Taylor, Hangpeng Li, Yaqing Zhao, Alisha Suri, Tom Sexton, James O. J. Davies, Jennifer A. Mitchell

The paper shows enhancers mediate euchromatin hopping, spreading euchromatin features to distal regions through chromatin looping, redefining enhancer identification using chromatin features.

bioRxiv · Sep 5, 2025 · PreprintMolecular Biology

THE CELLS ARE ALL-RIGHT: Regulation of the Lefty genes by separate enhancers in mouse embryonic stem cells

Tiegh Taylor, Hongyu Vicky Zhu, Sakthi D. Moorthy, Nawrah Khader, Jennifer A. Mitchell

The paper shows that Lefty1 and Lefty2 genes in mouse embryonic stem cells are regulated by separate enhancers despite being in the same TAD.

PLoS Genetics · Dec 13, 2024Peer-reviewedGenomics

Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding

Liangxi Wang, Tiegh Taylor, Kumaragurubaran Rathnakumar, Nadiya Khyzha, Minggao Liang, Azad Alizada, Laura Campitelli, Sara E. Pour, Zain M. Patel, Lina Antounians, Ian C. Tobias, Timothy R. Hughes, Sushmita Roy, Jennifer A. Mitchell, Jason E. Fish, Michael D. Wilson

The paper analyzes RELA-bound transposable elements across species to show their ancient and lineage-specific contributions to NF-κB binding and inflammation.

bioRxiv · Oct 25, 2022 · PreprintGenomics

A CREBZF/Zhangfei isoform activates CHOP during prolonged cellular stress

Yu Li, Wan Kong Yip, Jenna Penney, Tiegh Taylor, Yani Zhang, Minghua Zeng, Timothy E. Audas, Ray Lu

The paper identifies a CREBZF isoform, stZF, that activates CHOP during prolonged ER stress, promoting apoptosis and suggesting CREBZF's role in the Integrated Stress Response.

bioRxiv · Oct 10, 2022 · PreprintMolecular Biology

Transcriptional regulation and chromatin architecture maintenance are decoupled modular functions at the Sox2 locus

Tiegh Taylor, Natalia Sikorska, Virlana M. Shchuka, Sanjay Chahar, Chenfan Ji, Neil N. Macpherson, Sakthi D. Moorthy, Marit A. C. de Kort, Shanelle Mullany, Nawrah Khader, Zoe E. Gillespie, Lida Langroudi, Ian C. Tobias, Tineke Laura Lenstra, Jennifer A. Mitchell, Tom Sexton

The paper shows that transcriptional control and chromatin architecture at the Sox2 locus are decoupled, with distinct regulatory mechanisms.

Genes & Development · Jun 1, 2022Peer-reviewedGenetics