Author

Nicole Wetoska

University of Massachusetts Chan Medical SchoolORCID 0000-0003-3400-5873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Chloe DiMarzio· 2 shared Christopher B. NewgardiD· 2 shared Leslie A. RowlandiD· 2 shared Mark KellyiD· 2 shared Meixia PaniD· 2 shared Michael CzechiD· 2 shared Olga IlkayevaiD· 2 shared Xianlin HaniD· 2 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMolecular Biology

Chloe DiMarzio

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 25, 2022

De novo lipogenesis fuels adipocyte autophagosome membrane dynamics

Leslie A. Rowland, Adı́lson Guilherme, Felipe dos Santos Henriques…·Michael Czech

This study identifies de novo lipogenesis as a critical source of fatty acids for autophagosome membrane dynamics in adipocytes, showing that Fasn deficiency impairs autophagy and p62 degradation.

1 citation

mouseexperimental assay

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Molecular BiologybioRxivPreprintMar 21, 2022

Paradoxical activation of SREBP1c and de novo lipogenesis by hepatocyte-selective ACLY depletion in obese mice.

Batuhan Yenilmez, Mark Kelly, Guofang Zhang…·Michael Czech

The paper shows that ACLY depletion in obese mice paradoxically increases de novo lipogenesis despite reducing AcCoA levels, linked to increased SREBP1c expression.

3 citations

mousebulk RNA-seq

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