Leslie A. Rowland

This study shows that adipocyte Nrip1 deficiency in obese mice reduces hepatic steatosis and insulin resistance by promoting M2-like macrophages that secrete IL-1rn.

This study identifies Ncoa4 as a regulator of PPARγ activity and thermogenesis in brown adipose tissue through genetic and functional analyses.

This study identifies de novo lipogenesis as a critical source of fatty acids for autophagosome membrane dynamics in adipocytes, showing that Fasn deficiency impairs autophagy and p62 degradation.

The paper shows that ACLY depletion in obese mice paradoxically increases de novo lipogenesis despite reducing AcCoA levels, linked to increased SREBP1c expression.