Sabrina Liberatori

The paper identifies protein networks associated with virus-permissive and hostile cellular states through multi-omics analysis, revealing discrepancies between mRNA and protein levels and the role of phosphorylation in infection control.

This study shows that SIK1 activity modulates synaptic phosphoproteome to induce sleep independently of sleep pressure, revealing a causal mechanism for sleep regulation.

The paper shows that transcriptional changes during biological rhythms do not directly affect protein levels, which remain constant due to slow turnover rates and post-translational regulation.