Author

Anna F. Townley

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alex Appert· 1 shared Andrew AngeliD· 1 shared Anna Victoria ProtasioiD· 1 shared Benedikt Mathias KessleriD· 1 shared Charlotte L. GeorgeiD· 1 shared Emile RobertsiD· 1 shared Francesco Nicola CarelliiD· 1 shared Heli VaikkineniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Alex Appert

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2 papers

Recent·Most cited

Innate immune stress pathway activation underlies heterochromatin dysfunction pathology

Roopali Pradhan, Anna F. Townley, Anna Victoria Protasio, Joshua Miguel C. Danac, Yan Dong, Yushan Fang, Alex Appert, Francesco Nicola Carelli, Shixun Han, Heli Vaikkinen, Iva A. Tchasovnikarova, Julie Ahringer

The paper identifies activation of the innate immune stress pathway as a mechanism linking heterochromatin dysfunction to pathological phenotypes in C. elegans and human cells.

bioRxiv · Sep 26, 2026 · PreprintGenetics

Transcriptional changes are regulated by metabolic pathway dynamics but decoupled from protein levels

Jack Feltham, Shidong Xi, Struan C. Murray, Meredith Wouters, Julian Urdiain‐Arraiza, Raphael Heilig, Charlotte L. George, Anna F. Townley, Emile Roberts, Benedikt Mathias Kessler, Sabrina Liberatori, Philip D. Charles, Andrew Angel, Román Fischer, Jane Mellor

The paper shows that transcriptional changes during biological rhythms do not directly affect protein levels, which remain constant due to slow turnover rates and post-translational regulation.

bioRxiv · Jun 10, 2020 · PreprintMolecular Biology