Jiafeng Zhou

The paper identifies distinct developmental origins of neocortical astrocytes using multimodal techniques and reveals their unique lineage and developmental trajectory.

This study compares prenatal cortical development in two rodents, showing that major developmental milestones occur prenatally in Acomys, challenging the view that postnatal experience is essential for early brain maturation.

This study shows that loss of Lhx2 increases astrocyte proliferation in upper cortical layers and induces reactive gliosis-like signatures without injury.

This study maps the temporal transcriptomic changes in rhesus macaque neocortex during neurogenesis, revealing distinct lineage trajectories and signaling pathway divergence.

The paper identifies two distinct astrocyte lineages in the mouse neocortex using single-cell RNA sequencing and TrackerSeq, revealing their developmental origins and regulatory mechanisms.