This study presents a high-coverage whole-genome sequencing dataset of 1,171 admixed elderly Brazilians, identifying novel variants and demonstrating the utility of WGS for genomic and clinical research in underrepresented populations.

Nature Communications · Mar 4, 2022Peer-reviewedGenomics

Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass- and fat mass-indexes

Marília O. Scliar, Hanaisa P. Sant’Anna, Meddly L. Santolalla, Thiago Peixoto Leal, Nathalia Matta Araujo, Isabela Alvim, Víctor Borda, Wagner C. S. Magalhães, Mateus Henrique Gouveia, Ricardo Lyra, Moara Machado, Lucas A. Michelin, Maira Ribeiro Rodrigues, Gilderlânio Santana de Araújo, Fernanda S. G. Kehdy, , Eduardo Tarazona‐Santos

The paper identifies a West African-associated regulatory variant with a strong female-specific effect on BMI and fat mass in Brazilian admixed populations.

International Journal of Obesity · Feb 25, 2021Peer-reviewedGenetics

Origins, admixture dynamics and homogenization of the African gene pool in the Americas

Mateus Henrique Gouveia, Víctor Borda, Thiago Peixoto Leal, RENNAN GARCIA MOREIRA, Andrew W. Bergen, Fernanda S. G. Kehdy, Isabela Alvim, Marla Mendes de Aquino, Gilderlânio Santana de Araújo, Nathalia Matta Araujo, Vinícius Furlan, Raquel Liboredo, Moara Machado, Wagner C. S. Magalhães, Lucas A. Michelin, , Eduardo Tarazona‐Santos

The paper analyzes African genetic contributions to the Americas, showing regional ancestry patterns and admixture dynamics linked to historical factors.

Molecular Biology and Evolution · Feb 11, 2020Peer-reviewedGenetics