Patricia Montilla‐Perez

The paper develops FEDUPP, an open-source analysis pipeline, to assess learning and cognitive flexibility in mice using a home-cage paradigm, revealing subtle impairments in goal-directed feeding behavior.

This study examines sex-biased gene expression changes in mouse brain regions after adolescent THC exposure, identifying common regulatory mechanisms linked to cannabis use disorder vulnerability.

This study shows that Reelin deficiency increases cocaine-induced hyperlocomotion in mice by enhancing neuronal activity in the dorsomedial striatum, without affecting cocaine reward.

The paper investigates how drug exposure alters gene regulatory networks in the brain using multi-omics approaches, identifying enhancer repression and transcription factor involvement in addiction-related behaviors.

This study shows that Reelin deficiency exacerbates long-term behavioral issues in mice exposed to THC during adolescence, including impaired social behavior and increased novelty seeking.