Author

Leena Haataja

University of MichiganORCID 0000-0003-3701-4679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Peter R. ArvaniD· 2 shared Ajay H. ZalavadiaiD· 1 shared Ashleigh E. SchafferiD· 1 shared Bo‐Jhih Guan· 1 shared Boaz TiroshiD· 1 shared Cheikh A. Mbow· 1 shared Chien-Wen CheniD· 1 shared Clayton E. MathewsiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersSystems Biology

Peter R. ArvanORCID

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2 papers

Recent·Most cited

Systems BiologyNature CommunicationsPeer-reviewedAug 8, 2022

Adaptation to chronic ER stress enforces pancreatic β-cell plasticity

Chien-Wen Chen, Bo‐Jhih Guan, Mohammed R. Alzahrani…·Maria Hatzoglou

This study shows chronic ER stress induces β-cell plasticity, but excessive stress leads to identity loss and is linked to T1D progression.

116 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsScience AdvancesPeer-reviewedDec 4, 2019

Requirement for TRanslocon-Associated Protein (TRAP) α in insulin biogenesis

Xin Li, Omar A. Itani, Leena Haataja…·Patrick J Hu

This study identifies TRAP as essential for insulin biogenesis, showing it facilitates preproinsulin translocation and affects downstream processing and secretion.

35 citations

C. eleganshuman

𝕏 PostBluesky