Éric Rivals

This study identifies miR-4745 as a regulator of cancer stem cell traits in colorectal cancer, showing it inhibits CSC self-renewal and chemoresistance by targeting KLC2.

The paper presents algorithms for reconstructing past deletions in ancestral sequences using a deletion-only parsimony approach, providing exact solutions and graph-based representations of optimal reconstructions.

The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.

The paper introduces a Python package for efficiently searching di-PWM motifs in sequences, offering an easy-to-use interface and example scripts.

RNA-Ribo Explorer provides an interactive tool for analyzing and visualizing Ribo-seq data to explore translation dynamics and detect changes in RNA translation across conditions.

SHERPAS rapidly detects viral recombinants by analyzing phylogenetically-informed k-mers, outperforming existing methods in speed with minimal accuracy loss.

This study shows NF-Y maintains nucleosome-depleted regions at promoters to ensure accurate transcription initiation, preventing aberrant gene expression.

SAVAGE reconstructs individual haplotypes of intrahost viral strains without a reference genome, outperforming existing methods on simulated and real data.

The paper evaluates a model for inferring ancestral rearrangement scenarios by correlating Hi-C data clustering quality with rearrangement scenario accuracy between Drosophila species.