Author

Lotte Slenders

Utrecht UniversityORCID 0000-0003-3794-7604Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Gerard PasterkampiD· 3 shared Gert Jan de BorstiD· 3 shared Hester M. den RuijteriD· 3 shared Michal MokrýiD· 3 shared Arjan BoltjesiD· 2 shared Daniek KapteijniD· 2 shared Dominique P.V. de KleijniD· 2 shared Ernest Diez BenaventeiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Gerard PasterkampORCID

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3 papers

Recent·Most cited

Molecular BiologyVascular PharmacologyPeer-reviewedMay 1, 2025

Identification of endothelial-to-mesenchymal transition gene signatures in single-cell transcriptomics of human atherosclerotic tissue

Lotte Slenders, Marian Wesseling, Siting Wei…·Michal Mokrý

The paper identifies gene signatures of endothelial-to-mesenchymal transition in human atherosclerotic tissue using combined in vitro and single-cell transcriptomic data.

15 citations

humanscRNA-seq

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BioinformaticsArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedAug 17, 2023

Female gene networks are expressed in myofibroblast-like smooth muscle cells in vulnerable atherosclerotic plaques.

Ernest Diez Benavente, Santosh Karnewar, Michele F. Buono…·Hester M. den Ruijter

The paper identifies sex-stratified gene regulatory networks in atherosclerotic plaques, showing female plaques are enriched with myofibroblast-like smooth muscle cell networks.

35 citations

humanbulk RNA-seq

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GenomicsAtherosclerosisPeer-reviewedAug 1, 2021

Sex-dependent gene regulation of human atherosclerotic plaques by DNA methylation and transcriptome integration points to smooth muscle cell involvement in women.

Robin J. G. Hartman, Marten Antoon Siemelink, Saskia Haitjema…·Hester M. den Ruijter

10 citations

humanDNA methylation

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