Aybuke Alici-Garipcan

This paper constructs a single-cell atlas of uterine carcinosarcoma across diverse ancestries, revealing cancer cell plasticity and stromal-immune remodeling in primary and metastatic tumors.

This paper develops an ancestrally inclusive patient-derived organoid platform for UCS that captures cancer cell plasticity and identifies therapeutic vulnerabilities.

The paper investigates how different high-fat diets affect host and microbiome multi-omic states over time and shows that some changes persist even after returning to a control diet.

The paper shows that goblet and Paneth cells share similar gene expression and chromatin features, and their phenotypes are influenced by niche signals like BMP, suggesting a single cell type with plasticity.

This study shows NLRP7 regulates BMP4 signaling in trophoblast differentiation using patient-derived iPSCs, correcting excessive differentiation with BMP pathway inhibition.