Trevor John Kilpatrick

This study identifies conserved microglial miRNAs across species and their preserved function in demyelination and remyelination.

The paper investigates C4 genetic structural variations in multiple sclerosis, finding associations with disease risk and progression, and links them to immune cell expression and pathways.

This study identifies unique miRNA-mRNA networks in mouse microglia during CNS development and homeostasis, revealing their role in age-specific functions and disease states.

This paper develops a pharmacogenetic model to ablate oligodendrocyte progenitor cells (OPCs) in adult mice, achieving 98.6% depletion and revealing compensatory mechanisms from V-SVZ-derived NPCs.

The paper analyzes somatic mutations in neurons and oligodendrocytes from MS patients, finding increased DNA damage linked to inflammation.

This study identifies a unique BOLD signal in white matter using fMRI and shows reduced signal power in multiple sclerosis patients, linking neuroinflammation to vascular dysfunction.