Author
The University of MelbourneORCID 0000-0002-5552-2469Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Indu Raman, Cavan Bennett, Sant-Rayn Pasricha, Ricardo Ataide, Anne Pettikiriarachchi, Jumana Yousef, Laura F Gianni, Costas K Yannakou, Samantha J Emery-Corbin, Ellen Tsui, Yu Zhu, Pradeep Rajasekhar, Allan Motyer, Surender Juneja, Sukhdeep Spall
The paper performs proteomic analysis of megakaryocytes in MPN patients and identifies disease-specific proteomic signatures.
bioRxiv · Nov 2, 2026 · PreprintCancer Biology
Ashleigh N. Solano, Raymond K. H. Yip, Changqing Wang, Daniela Amann‐Zalcenstein, Pradeep Rajasekhar, Ishrat Zaman, Allan Motyer, Marek Cmero, Yang Xu, Yining Pan, Casey J. A. Anttila, Stephanie I. Studniberg, Peter F. Hickey, Layla Wang, Callum J. Sargeant, , Matthew E. Ritchie
SpatialBench evaluates spatial transcriptomics platforms using a mouse spleen model, finding consistent biological signals but varying resolution across technologies.
bioRxiv · May 1, 2026 · PreprintBioinformatics
Allan Motyer, Stacey Jackson, Bicheng Yang, Ivon Harliwong, Wei Tian, Wingin Shiu, Yunchang Shao, Bo Wang, Catriona McLean, Michael Harry Barnett, Trevor John Kilpatrick, Stephen Leslie, Justin P. Rubio
The paper analyzes somatic mutations in neurons and oligodendrocytes from MS patients, finding increased DNA damage linked to inflammation.
bioRxiv · Apr 30, 2022 · PreprintGenomics
Frauke C. Degenhardt, Gabriele Mayr B, Mareike Wendorff, Gabrielle Boucher, Eva Ellinghaus, David Ellinghaus, Hesham ElAbd, Elisa Rosati, Matthias Hübenthal, Simonas Juzėnas, Shifteh Abedian, Homayon Vahedi, Bittianda Kuttapa Thelma, Suk‐Kyun Yang, Byong Duk Ye, , André Franke
This study identifies shared and ethnicity-specific HLA associations with ulcerative colitis through trans-ethnic analysis of diverse populations.
Human Molecular Genetics · Jan 12, 2021Peer-reviewedGenetic & Genomic Medicine
David Squire, Allan Motyer, Richard S. Ahn, Joanne Nititham, Zhiming Huang, Jorge R. Oksenberg, John Foerster, Wilson J. Liao, Stephen Leslie
MHC*IMP imputes alleles for MHC genes using a reference panel and SNP data, achieving high accuracy in allele prediction.
bioRxiv · Jan 24, 2020 · PreprintGenomics
Adrián Cortés, Calliope Athena Dendrou, Allan Motyer, Luke Jostins, Damjan Vukcevic, Alexander Dilthey, Peter Donnelly, Stephen Leslie, Lars H. Fugger, Gil McVean
This paper develops a Bayesian framework to analyze genetic associations with healthcare phenotypes in the UK Biobank, identifying over 2,000 diagnostic term associations and novel immune-mediated disease links.
Nature Genetics · Jul 31, 2017Peer-reviewedGenetics
Clare Bycroft, Colin Freeman, Desislava Petkova, Gavin Band, Lloyd T. Elliott, Kevin Sharp, Allan Motyer, Damjan Vukcevic, Olivier Delaneau, Jared O’Connell, Adrián Cortés, Samantha Welsh, Gil McVean, Stephen Leslie, Peter Donnelly, Jonathan Marchini
Quality-controlled genotypes for 488,377 UK Biobank participants at 805,426 markers, imputed to ~96 million variants, plus ancestry PCs, kinship (30.3% have close relatives enrolled) and HLA calls.
bioRxiv · Jul 20, 2017 · PreprintGenetics✦ In-depth digest
Allan Motyer, Damjan Vukcevic, Alexander Dilthey, Peter Donnelly, Gil McVean, Stephen Leslie
The paper evaluates HLA imputation methods using a multi-ethnic panel, introduces a new method HLA*IMP:03, and shows it achieves high accuracy without requiring probability thresholds.
bioRxiv · Dec 9, 2016 · PreprintGenetics