Author

Callum J. Dickson

ORCID 0000-0003-4013-6394Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Maryam KhoshoueiiD· 2 shared Alexander N.R. WeberiD· 1 shared Alfred G. ZimmerliniD· 1 shared Andreas HofmanniD· 1 shared Artiom CernijenkoiD· 1 shared Ashley A. Burke· 1 shared Aude Sylvain· 1 shared Azeddine ElhajoujiiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Maryam KhoshoueiORCID

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3 papers

Recent·Most cited

ImmunologyCell chemical biologyPeer-reviewedJul 1, 2025

A cereblon (CRBN) molecular glue degrader of NIMA-related kinase 7 (NEK7) reveals a context-dependent role in NLRP3 inflammasome activation

Aude Sylvain, Natacha Stoehr, Fupeng Ma…·Zuni I. Bassi

This paper identifies NK7-902, a CRBN molecular glue degrader of NEK7, showing partial inhibition of NLRP3 inflammasome activation in humans and full activity in mice, but only transient effects in non-human primates.

27 citationstop 2%

humanmouse

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BiochemistrybioRxivPreprintApr 12, 2025

An analysis of free energy methods to quantify and displace the KRasG12D Thr58 water

Callum J. Dickson

The paper evaluates free energy methods for quantifying and displacing a conserved water molecule in KRasG12D inhibitors.

DOI 10.1101/2025.04.12.648534

humanprotein structure

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BiophysicsStructurePeer-reviewedAug 23, 2024

Scorpion α-toxin LqhαIT specifically interacts with a glycan at the pore domain of voltage-gated sodium channels

Swastik Phulera, Callum J. Dickson, Christopher J. Schwalen…·Wilhelm Andreas Weihofen

This study determines the cryo-EM structure of LqhIT bound to NavPas, revealing its interaction with a glycan at the pore domain and its mechanism of action.

6 citations

structural biologyexperimental assay

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