Jason C. Bartz

This paper demonstrates that the G127V prion protein variant can prevent and suppress prion infection through a dominant-negative effect, suggesting its potential as a therapeutic strategy.

The paper investigates whether DNA extraction methods co-purify prions, finding that commercial kits do not eliminate prion seeding activity, posing biosafety risks.

This study investigates co-infection with two α-synuclein strains in mice, finding synergistic interactions that accelerate disease progression.

This study demonstrates that CWD prions can contaminate processing surfaces and be transferred to CWD-negative venison, but can be inactivated using bleach and potassium peroxymonosulfate.

The paper describes a protocol for a prion safety laboratory swipe test to assess contamination and decontamination effectiveness in lab settings.