Jing Qiu

The paper identifies NRF2 activation in mononuclear myeloid cells as a protective response to intracerebral haemorrhage, showing its therapeutic potential through modulation of interferon pathways.

This study shows astrocytes alter the transcriptomic and epigenetic landscape of developing cortical neurons, promoting intrinsic excitability and influencing disease-related pathways.

This study identifies new ADAM9 substrates and downstream pathways using an integrative proteotranscriptomics approach in HCT116 cells.

This study investigates the cell-type-specific role of Nrf2 in regulating transcriptional signatures and inflammatory responses in the adult mouse brain.

This paper shows that endothelial cell Nrf2 activation reduces neuroinflammation caused by systemic inflammation.

This study shows that neurodevelopmental processes in the cortex and thalamus can occur normally without microglia, using a genetically modified mouse model.

This study shows microglia promote beta-amyloid plaque formation but are not required for subsequent pathological changes in Alzheimer's disease.

The paper compares human and mouse exon usage in cortical neurons, finding conservation in basal inclusion but divergence in activity-dependent usage, suggesting both cis-acting and trans-acting factors contribute to species differences.