Author

Tom Leah

UK Dementia Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Jing QiuiD· 2 shared Owen DandoiD· 2 shared Xin HeiD· 2 shared Adrian Higginbottom· 1 shared Agnieszka N. UrbanekiD· 1 shared Alfredo Gonzalez‐SulseriD· 1 shared Andrea CaporaliiD· 1 shared Anna OlerinyovaiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Jing QiuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Endothelial cell Nrf2 controls neuroinflammation following a systemic insult

Haoyu Zou, Tom Leah, Zhuochun Huang, Xin He, Eleonora Mameli, Andrea Caporali, Owen Dando, Jing Qiu

This paper shows that endothelial cell Nrf2 activation reduces neuroinflammation caused by systemic inflammation.

iScience · May 12, 2025Peer-reviewedNeuroscience

Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus

Mary O’Keeffe, Sam A. Booker, Darren A. Walsh, Mosi Li, Chloe Henley, Laura Simões de Oliveira, Mingshan Liu, Xingran Wang, María Banqueri, Katherine Ridley, Kosala N. Dissanayake, Cristina Martinez‐Gonzalez, Kirsty J. Craigie, Deepali Vasoya, Tom Leah, , Giles E. Hardingham

This study shows that neurodevelopmental processes in the cortex and thalamus can occur normally without microglia, using a genetically modified mouse model.

Nature Neuroscience · Jan 6, 2025Peer-reviewedNeuroscience

Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease

Zengjie Xia, Emily E. Prescott, Agnieszka N. Urbanek, Hollie E. Wareing, Marianne C. King, Anna Olerinyova, Helen Dakin, Tom Leah, Katy Barnes, Martyna M. Matuszyk, Eleni Dimou, Eric Hidari, Yu P. Zhang, Jeff Y. L. Lam, John S. H. Danial, , Suman De

The paper shows that apoE isoforms modulate Aβ aggregation, clearance, and toxicity in Alzheimer's disease, with implications for therapeutic strategies.

Nature Communications · Jun 1, 2024Peer-reviewedNeuroscience