Kevin J. Mastro

This study develops a behavioral platform to study decision making in marmosets and finds that reward predictability influences behavioral states and error correction during task performance.

The paper identifies two distinct electrophysiological and molecular phenotypes of pallidocortical neurons projecting to motor and non-motor cortical regions, revealing a closed-loop circuit between the GPe and cortex.

This study shows that frontal cortical circuits in mice continue to mature beyond sexual maturity, affecting decision-making behaviors with age.

This study shows that microglia and complement proteins drive early synapse loss and cognitive deficits in Huntington's disease by eliminating corticostriatal synapses, and that targeting this pathway can prevent these effects.

The paper identifies enhancers for targeting specific neuronal subtypes across species and demonstrates their utility in circuit manipulation.