Kie Itoh

The paper uses zap-and-freeze electron microscopy to study synaptic vesicle dynamics in mouse and human brain slices, revealing conserved endocytic mechanisms.

This study identifies Doc2 as the major Ca2+ sensor for asynchronous release and shows that syt7 supports vesicle docking, with combined effects on synaptic function.

The paper shows that Dynamin 1xA forms molecular condensates with Syndapin 1 at endocytic sites, enabling ultrafast endocytosis by bypassing the recruitment step.

The paper shows that Dynamin 1xA and Syndapin 1 form liquid-like condensates at synapses, which facilitate ultrafast endocytosis by enabling molecular crowding and intermolecular interactions.