Cell BiologybioRxivPreprint
Peroxiredoxin 6 limits mitochondrial peroxidation to prevent mitochondrial ER contact site assembly and inflammatory signalling following adaptive stress
Penglin Li, Yating Zheng, Jiwang Tang…·Brian McDonagh
This study shows PRDX6 limits mitochondrial lipid peroxidation under oxidative stress, preventing MERCS formation and inflammation in both myoblasts and C. elegans.
DOI 10.64898/2026.07.24.740509